Albiglutide in type 2 diabetes: Hint of minor added benefit

Study data for a combination with metformin show a hint of a minor added benefit because symptomatic hypoglycemia occurs less frequently, experts report after an investigation.

Could gut microbes help treat brain disorders? Mounting research tightens their connection with the brain

The community of microbes that inhabits the body, known as the microbiome, has a powerful influence on the brain and may offer a pathway to new therapies for psychiatric and neurological disorders, according to researchers.

Exposure to nanoparticles may threaten heart health

While nanotechnology has led to countless advancements, a group of researchers is now raising a flag of caution about its effects on our health. They say exposure to tiny silica-based particles can play a big role in increasing heart attack and stroke risks.

Mapping snake venom variety reveals unexpected evolutionary pattern

Venom from an eastern diamondback rattlesnake in the Everglades is distinct from the cocktail of toxins delivered by the same species in the Florida panhandle area, some 500 miles away. But no matter where you go in the Southeastern United States, the venom of the eastern coral snake is always the same. The results challenge common assumptions in venom evolution research, provide crucial information for rattlesnake conservation, and will help coral snake antivenom development.

Nutrient sensor in key growth-regulating metabolic pathway identified

For the first time, scientists have identified a protein that appears to be a nutrient sensor for the key growth-regulating mTORC1 metabolic pathway.

Brain imaging may help predict future behavior

Noninvasive brain scans have led to basic science discoveries about the human brain, but they've had only limited impacts on people's day-to-day lives. A review article highlights a number of recent studies showing that brain imaging can help predict an individual's future learning, criminality, health-related behaviors, and response to drug or behavioral treatments. The technology may offer opportunities to personalize educational and clinical practices.

Epigenomics analysis reveals surprising new clues to insulin resistance

In studying the cellular structure and function of insulin, a research team has uncovered previously unknown steps in the development of insulin resistance. Previous investigations of insulin resistance have focused almost exclusively on proteins and cellular functions at or near the surface of cells, where insulin binds. However, epidemiological and molecular data have suggested that events leading to insulin resistance might also take place in the nucleus, where the DNA blueprint is stored.